Connect with us

Start-Ups

YC startup Felix wants to replace antibiotics with programmable viruses

Published

on

YC startup Felix wants to replace antibiotics with programmable viruses

Right now the world is at conflict. But that is no bizarre conflict. It’s a combat with an organism so small we are able to solely detect it by way of use of a microscope — and if we don’t cease it, it may kill hundreds of thousands of us within the subsequent a number of many years. No, I’m not speaking about COVID-19, although that organism is the one on everybody’s thoughts proper now. I’m speaking about antibiotic-resistant micro organism.

You see, greater than 700,000 folks died globally from bacterial infections final yr — 35,000 of them within the U.S. If we do nothing, that quantity may develop to 10 million yearly by 2050, in line with a United Nations report.

The drawback? Antibiotic overuse on the physician’s workplace or in livestock and farming practices. We used a number of medicine over time to kill off all of the dangerous micro organism — nevertheless it solely killed off most, not all, of the dangerous micro organism. And, because the well-known line from Jeff Goldblum in Jurassic Park goes, “life finds a manner.”

Enter Felix, a biotech startup within the newest Y Combinator batch that thinks it has a novel method to protecting bacterial infections at bay – viruses.

Phage killing micro organism in a petri dish

It appears bizarre in a time of widespread concern over the corona virus to be any virus in a great mild however as co-founder Robert McBride explains it, Felix’s key know-how permits him to focus on his virus to particular websites on micro organism. This not solely kills off the dangerous micro organism however also can halt its means to evolve and as soon as extra turn out to be resistant.

READ MORE:  Medical robotics has an incredible future: French startup Robocath secures €40M funding to deploy operations

But the concept to make use of a virus to kill off micro organism will not be essentially new. Bacteriophages, or viruses that may “infect” micro organism, had been first found by an English researcher in 1915 and commercialized phage remedy started within the U.S. within the 1940’s by way of Eli Lilly and Company. Right about then antibiotics got here alongside and Western scientists simply by no means appeared to discover the remedy additional.

However, with too few new options being provided and the usual drug mannequin not working successfully to fight the scenario, McBride believes his firm can put phage remedy again on the forefront.

Already Felix has examined its resolution on an preliminary group of 10 folks to show its method.

Felix researcher serving to cystic fibrosis affected person Ella Balasa by way of phage remedy

“We can develop therapies in much less time and for much less cash than conventional antibiotics as a result of we’re focusing on orphan indications and we already know our remedy can work in people,” McBride advised TechCrunch . “We argue that our method, which re-sensitizes micro organism to conventional antibiotics may very well be a primary line remedy.”

Felix plans to deploy its remedy for bacterial infections in these affected by cystic fibrosis first as these sufferers are inclined to require a close to fixed stream of antibiotics to fight lung infections.

READ MORE:  Finance on phone: Amsterdam fintech startup with Russian roots secures €6.5M funding

The subsequent step will likely be to conduct a small scientific trial involving 30 folks, then, because the scientific analysis and improvement mannequin tends to go, a bigger human trial earlier than in search of FDA approval. But McBride hopes his viral resolution will show itself out in time to assist the approaching onslaught of antibiotic resistance.

“We know the antibiotic resistant problem is giant now and is just going to worsen,” McBride stated. “We have a sublime technological resolution to this problem and we all know our remedy can work. We need to contribute to a future through which these infections don’t kill greater than 10 million folks a yr, a future we are able to get enthusiastic about.”

Continue Reading
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

As wildfire season approaches, AI could pinpoint risky regions using satellite imagery
Tech28 mins ago

As wildfire season approaches, AI could pinpoint risky regions using satellite imagery

Jeremy Conrad left his own VC firm to start a company, and investors like what he’s building
Start-Ups34 mins ago

Jeremy Conrad left his own VC firm to start a company, and investors like what he’s building

Ricky Powell: The Individualist Trailer
Entertainment45 mins ago

Official Trailer for Photographer Doc 'Ricky Powell: The Individualist'

D The Mandalorian Teaser Tall A
Entertainment3 hours ago

The Alternate Universe ‘Star Wars’ Live-Action TV Series

ERC-20 Tokens Now Make up Almost 50% of the Total Value Stored on Ethereum
Crypto3 hours ago

ERC-20 Tokens Now Make up Almost 50% of the Total Value Stored on Ethereum

Salesforce stock is taking a hit today after lighter guidance in yesterday’s earning’s report
Tech3 hours ago

Salesforce stock is taking a hit today after lighter guidance in yesterday’s earning’s report

Why millions of Americans are getting coronavirus stimulus payments on scammy-looking debit cards
Tech4 hours ago

Why millions of Americans are getting coronavirus stimulus payments on scammy-looking debit cards

YouTube Video
Entertainment5 hours ago

‘Knight of Cups’ Deserves a Second Look

3 ways European startups can win with innovation in the COVID-19 era
Start-Ups6 hours ago

3 ways European startups can win with innovation in the COVID-19 era

How to upgrade your at-home videoconference setup: Lighting edition
Tech7 hours ago

How to upgrade your at-home videoconference setup: Lighting edition

Be Water Doc Trailer
Entertainment7 hours ago

Learn the Complete Story of Bruce Lee in Doc Film 'Be Water' Trailer

Coronavirus Social Distancing
Tech8 hours ago

This Google app will help keep you safe from coronavirus

Reddcoin (RDD) Nears PoSV v2 Activation, Clearing Way for Explosive Developments
Crypto8 hours ago

Reddcoin (RDD) Nears PoSV v2 Activation, Clearing Way for Explosive Developments

Darth Vader
Entertainment9 hours ago

Vocal Performances Deserve More Recognition

Cisco to acquire internet monitoring solution ThousandEyes
Tech10 hours ago

Cisco to acquire internet monitoring solution ThousandEyes

The secret to trustworthy data strategy
Start-Ups11 hours ago

The secret to trustworthy data strategy

Pixel 4a Release Date
Tech11 hours ago

Google canceled a next-gen Pixel phone, but photos just leaked anyway

Star Light Trailer
Entertainment11 hours ago

First Trailer for Horror Film 'Star Light' with Scout Taylor-Compton

Twitter screens Trump’s Minneapolis threat-tweet for glorifying violence
Tech13 hours ago

Twitter screens Trump’s Minneapolis threat-tweet for glorifying violence

Attack Of The Demons
Entertainment13 hours ago

Celebrating the Best of the Chattanooga Film Festival 2020

‘America needs our help’: Q&A with OfferUp CEO Nick Huzar after Seattle-area startup lands $120M
Tech2 months ago

‘America needs our help’: Q&A with OfferUp CEO Nick Huzar after Seattle-area startup lands $120M

Dr. Pimple Popper Goes Too Far For Some Fans With Blackhead Rice Krispie Treats Baking Video!
Entertainment2 months ago

Dr. Pimple Popper Goes Too Far For Some Fans With Blackhead Rice Krispie Treats Baking Video!

Global Savings Group acquires French cashback company iGraal for €123.5M
Start-Ups2 months ago

Global Savings Group acquires French cashback company iGraal for €123.5M

Updated FDA COVID-19 testing guidelines specifically disallow at-home sample collection
Start-Ups2 months ago

Updated FDA COVID-19 testing guidelines specifically disallow at-home sample collection

All Day and a Night Trailer
Entertainment1 month ago

Trailer for 'All Day and a Night' with Jeffrey Wright & Ashton Sanders

Fiat Chrysler to start producing 1 million face masks a month
Tech2 months ago

Fiat Chrysler to start producing 1 million face masks a month

Jennifer Lopez’s High School Sweetheart Dead At 51
Entertainment2 months ago

Jennifer Lopez’s High School Sweetheart Dead At 51

Former Slack exec April Underwood has joined Obvious Ventures as a venture partner
Tech2 months ago

Former Slack exec April Underwood has joined Obvious Ventures as a venture partner

Where top VCs are investing in D2C
Tech2 months ago

Startups Weekly: A new era for consumer tech

The Main Event Trailer
Entertainment2 months ago

Seth Carr Becomes a Wrestler in Fun Trailer for 'The Main Event' Film

Oura partners with UCSF to determine if its smart ring can help detect COVID-19 early
Start-Ups2 months ago

Oura partners with UCSF to determine if its smart ring can help detect COVID-19 early

Amazon Prime delivery delays are now as long as a month
Tech2 months ago

Amazon Prime delivery delays are now as long as a month

Kinsa’s fever map could show just how crucial it is to stay home to stop COVID-19 spread
Tech2 months ago

Kinsa’s fever map could show just how crucial it is to stay home to stop COVID-19 spread

Streaming service fuboTV to merge with virtual entertainment technology company, FaceBank
Tech2 months ago

Streaming service fuboTV to merge with virtual entertainment technology company, FaceBank

The Google and Verily coronavirus websites are off to a rocky start
Tech2 months ago

The Google and Verily coronavirus websites are off to a rocky start

‘Canary in a coal mine’: Seattle marketing tech startup Amplero shuts down, lays off 17 employees
Tech2 months ago

‘Canary in a coal mine’: Seattle marketing tech startup Amplero shuts down, lays off 17 employees

After Life
Entertainment2 months ago

What’s New to Stream on Netflix for April 2020, and What’s Leaving

Rocket Lab postpones next mission due to coronavirus pandemic
Tech2 months ago

Rocket Lab postpones next mission due to coronavirus pandemic

Lime’s valuation, variable costs and diverging categories of on-demand companies
Tech2 months ago

Lime’s valuation, variable costs and diverging categories of on-demand companies

RESISTANCE_movie review jesse eisenberg (1)
Entertainment2 months ago

‘Resistance’ Shows Untold Heroism of Iconic French Mime

Trending